Endocannabinoids

the brain and body"s marijuana and beyond
  • 563 Pages
  • 3.33 MB
  • 5195 Downloads
  • English

Taylor & Francis/CRC Press , Boca Raton, FL
Statementedited by Emmanuel S. Onaivi, Takayuki Sugiura, Vincenzo di Marzo.
Classifications
LC ClassificationsQP
The Physical Object
Pagination563 p. :
ID Numbers
Open LibraryOL22718412M
ISBN 100415300088

Product details Hardcover: pages Publisher: CRC Press; 1 edition (November 1, ) Language: English ISBN ISBN Product Dimensions: 7 x x 10 inches Shipping Weight: pounds (View shipping rates and policies) Customer Reviews: out of 4/5(1).

Description Endocannabinoids FB2

Product details Hardcover: pages Publisher: Academic Press; 1 edition ( ) Language: English ISBN ISBN Product Dimensions: x x 9 inches Shipping Weight: pounds (View shipping rates and policies) Customer Reviews: out of 5/5(1).

The first book of its kind, The Endocannabinoidome is a meaningful reference for all those involved in experimental efforts to further the development of this field. Key Features Explores the novel and exciting aspects of several endocannabinoid-like molecules for which researchers are still seeking a function.

Purchase The Endocannabinoid System - 1st Edition. Print Book & E-Book. ISBNBook description. The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system.

read full description. The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early s by researchers exploring THC, a well-known cannabinoid.

Cannabinoids are compounds found in : Crystal Raypole. Dr. Mechoulam’s world-changing research discovered two main receptors, cannabinoid 1 (CB1) and cannabinoid 2 (CB2), that are keyed to both the endocannabinoids that our body naturally produces and phytocannabinoids (plant-based) like THC and CBD.

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Our bodies actually produce the ECs similar to how our body produces narcotic-like endorphins. The human endocannabinoid system is made up of three main components: cannabinoid receptors, endocannabinoids, and the enzymes that break them down.

This system is present throughout the Endocannabinoids book body — it’s on immune cells in our bloodstream, all over our nervous systems, on the entire axis of the spinal cord, and in virtually every cell in.

Endocannabinoids and Neurodegenerative Disorders: Parkinson’s Disease, Huntington’s Chorea, Endocannabinoids book Disease, and Others Pages Fernández-Ruiz, Javier (et al.). Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology.

It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and Edition: 1st Edition. Cannabinoids and the Endocannabinoid System Franjo Grotenhermen nova-Institut, Goldenbergstraße 2, D Hürth, Germany Abstract The human body possesses specific binding sites on the surface of many cell types Endocannabinoids book cannabi-noids, and our body produces several endocannabinoids, fatty acid derivatives that bind to these.

Two primary cell receptors make up the ECS, Cannabinoid Receptor 1 (CB1) and Cannabinoid Receptor 2 (CB2). The keys to these receptors are called endocannabinoids. Endocannabinoids are Endocannabinoids book the body’s natural THC.

In fact, endocannabinoids got their name from cannabis. Plant cannabinoids were discovered first. About this book ‘Cannabinoids’ is a broad term covering a group of natural products from Cannabis sativa, one of which locks on to specific receptors – protein molecules on the surface of cells – known as cannabinoid receptors.

Endocannabinoids: Molecular, Pharmacological, Behavioral and Clinical Features;is a monograph that presents interesting manuscripts selected by the editor on the subject. Chapters in this book include original research or reviews which report the relevance of the endocannabinoid system by describing the results of experimental evidence about Cited by: 1.

The endocannabinoid system is a biological system which plays many important roles in the human body. It is also responsible for the physical and psychological effects of cannabis. Scientists first discovered the system while trying to understand the effects of cannabis, and named it the endocannabinoid system for this reason.

About this book Introduction There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced “autoprotection”, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced “autoimpairment”.

Introduction to the Endocannabinoid System Ethan Russo, MD Medical Director, PHYTECS The endocannabinoid system (ECS) is an essential regulator of bodily function in its many facets. There is hardly any physiological process that is not affected by it to some degree. This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research.

Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their Brand: Springer New York.

Emmanuel S. Onaivi, Ph.D, Professor of Biology, William Paterson University, will be Keynote, presenting his pioneering research on cannabis, its constituent cannabinoids and the natural cannabis compounds produced by the human body called endocannabinoids.

Abstract. The endocannabinoid system consists of G protein-coupled cannabinoid CB 1 and CB 2 receptors, of endogenous compounds known as endocannabinoids that can target these receptors, of enzymes that catalyse endocannabinoid biosynthesis and metabolism, and of processes responsible for the cellular uptake of some endocannabinoids.

This review presents in vitro evidence that most or all Cited by:   This article has been cited byother articles in PMC. The endocannabinoid system is a unique neuromodulatory system in mammalian physiology.

It consists of cannabinoid receptors (CB1 and CB2), their endogenous lipid ligands [endocannabinoids, including anandamide (AEA), and 2-arachidonoylglycerol (2-AG)] and the enzymes for ligand synthesis and by: Endocannabinoids, the latest volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into the neurobiology of migraines.

It reviews the current knowledge and understanding in the field, and provides a starting point for researchers and practitioners entering the field.

An interesting twist on the steric selectivity of cannabinoid receptors has emerged through recent studies of the behaviorally inactive phytocannabinoid (−)-cannabidiol (CBD) and its synthetic analogs, which have negligible affinity for either CB 1 or CB 2 receptors.

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Paradoxically, some of the synthetic (+)-(+)-stereoisomers of these compounds were found to bind potently to both CB 1 and CB. ISBN: OCLC Number: Description: xii, pages: illustrations (chiefly color) ; 24 cm. Contents: Endocannabinoids and their pharmacological actions / Roger G.

Pertwee --Biosynthesis and fate of endocannabinoids / Maria Grazia Cascio, Pietro Marini --Distribution of the endocannabinoid system in the central nervous system / Sherry Shu-Jung Hu, Ken. Endocannabinoids. likes.

Endocannabinoids are cannabinoids produced naturally by humans and other animals. They "are involved in a variety of physiological processes including appetite, Followers: What Is The Endocannabinoid System. The ECS is made up of cannabinoid receptors, endocannabinoids (chemical compounds made within the body) and enzymes that break down these endocannabinoids.

Located in the brain, connective tissue, glands, organs and immune cells, the ECS effectively impacts the whole body to create a stable internal environment regardless of the changing.

Since the discovery of the Endocannabinoid System in the late ’s, researchers have learned more and more about the synergistic relationship between phytocannabinoids and endocannabinoids. Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology.

It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and 5/5(1). Endocannabinoids serve as intercellular 'lipid messengers', signaling molecules that are released from one cell and activating the cannabinoid receptors present on other nearby cells.

Although in this intercellular signaling role they are similar to the well-known monoamine neurotransmitters such as dopamine, endocannabinoids differ in. A review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic use.

The cannabis plant has been used for recreational and medicinal purposes for more than 4, years, but the scientific investigation into its effects has only recently yielded useful results. In this book, Linda Parker offers a review of the. Endocannabinoids. by. Handbook of Experimental Pharmacology (Book ) Share your thoughts Complete your review.

Tell readers what you thought by rating and reviewing this book. Rate it Brand: Springer International Publishing.

Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes.

This article provides an overview of this emerging by:   The endocannabinoid system is known to be located and involved broadly in the body.

This includes the central and peripheral nervous systems, immune system, and most organs, tissues, and glands, spanning critical functions of physiology, behavior, immunology, and metabolism.